Murray Barclay




Conference Contribution - Published proceedings: Abstract

Wright, D. F. B., Duffull, S. B., Merriman, T. R., Barclay, M. L., & Stamp, L. K. (2015). Allopurinol dosing in patients with renal impairment. Proceedings of the Twenty-Fourth Annual Meeting of the Population Approach Group in Europe (PAGE)., 3338. Retrieved from

Wright, D. F. B., Merriman, T. R., Duffull, S. B., Barclay, M. L., & Stamp, L. K. (2014). The relationship between fractional urate clearance and renal transporter genotype in patients with gout. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) and the Molecular Pharmacology of G Protein-Coupled Receptors (MPGPCR) Joint Scientific Meeting., (pp. 47). Retrieved from

Barclay, M. L., Helms, E., Hock, B., Schultz, M., & Stamp, L. K. (2014). Trough concentrations of infliximab and adalimumab, and anti-drug antibodies, correlate with drug response in inflammatory bowel disease. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) and the Molecular Pharmacology of G Protein-Coupled Receptors (MPGPCR) Joint Scientific Meeting., (pp. 25). Retrieved from


Conference Contribution - Verbal presentation and other Conference outputs

Barclay, M. (2014, August). Infliximab and adalimumab trough concentrations and anti-drug antibodies correlate with response in inflammatory bowel disease. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand.


Journal - Research Article

Doecke, J. D., Simms, L. A., Zhao, Z. Z., Roberts, R. L., Fowler, E. V., Croft, A., … Barclay, M. L., Merriman, T. R., Gearry, R. B., … Radford-Smith, G. L. (2015). Smoking behaviour modifies IL23r-associated disease risk in patients with Crohn's disease. Journal of Gastroenterology & Hepatology,30(2), 299-307. doi: 10.1111/jgh.12674

Chua, E. W., Cree, S., Barclay, M. L., Doudney, K., Lehnert, K., Aitchison, A., & Kennedy, M. A. (2015). Exome sequencing and array-based comparative genomic hybridisation analysis of preferential 6-methylmercaptopurine producers. Pharmacogenomics Journal. Advance online publication. doi: 10.1038/tpj.2015.9

Stamp, L. K., Merriman, T. R., Barclay, M. L., Singh, J. A., Roberts, R. L., Wright, D. F. B., & Dalbeth, N. (2014). Impaired response or insufficient dosage? Examining the potential causes of ”inadequate response” to allopurinol in the treatment of gout. Seminars in Arthritis & Rheumatism44(2), 170-174.doi: 10.1016/j.semarthrit.2014.05.007

Stamp, L. K., & Barclay, M. (2014). Therapeutic drug monitoring in rheumatic diseases: Utile or futile?Rheumatology53(6), 988-997. doi: 10.1093/rheumatology/ket355

Pan, S., Stamp, L. K., Duffull, S. B., Barclay, M. L., Dalrymple, J. M., Drake, J., Zhang, M., Korell, J. (2014). Assessment of the relationship between methotrexate polyglutamates in red blood cells and clinical response in patients commencing methotrexate for rheumatoid arthritis. Clinical Pharmacokinetics. Advance online publication. doi: 10.1007/s40262-014-0179-5

Korell, J., Duffull, S. B., Dalrymple, J. M., Drake, J., Zhang, M., Barclay, M. L., & Stamp, L. K. (2014). Comparison of intracellular methotrexate kinetics in red blood cells with the kinetics in other cell types.British Journal of Clinical Pharmacology77(3), 493-497. doi: 10.1111/bcp.12209

Chin, P. K. L., Wright, D. F. B., Zhang, M., Wallace, M. C., Roberts, R. L., Patterson, D. M., Jensen, B. P., Barclay, M. L., Begg, E. J. (2014). Correlation between trough plasma dabigatran concentrations and estimates of glomerular filtration rate based on creatinine and cystatin C. Drugs in R&D14(2), 113-123.doi: 10.1007/s40268-014-0045-9

Chin, P. K. L., Patterson, D. M., Zhang, M., Jensen, B. P., Wright, D. F. B., Barclay, M. L., & Begg, E. J. (2014). Coagulation assays and plasma fibrinogen concentrations in real-world patients with atrial fibrillation treated with dabigatran. British Journal of Clinical Pharmacology78(3), 630-638. doi: 10.1111/bcp.12366

Buffery, P. J., Allen, K. M., Chin, P. K. L., Moore, G. A., Barclay, M. L., & Begg, E. J. (2014). Thirteen years' experience of pharmacokinetic monitoring and dosing of busulfan: Can the strategy be improved?Therapeutic Drug Monitoring36(1), 86-92. doi: 10.1097/FTD.0b013e31829dc940

Zhang, M., Moore, G. A., Barclay, M. L., & Begg, E. J. (2013). A simple high-performance liquid chromatography method for simultaneous determination of three triazole antifungals in human plasma.Antimicrobial Agents & Chemotherapy57(1), 484-489. doi: 10.1128/aac.00768-12

Wright, D. F. B., Stamp, L. K., Merriman, T. R., Barclay, M. L., Duffull, S. B., & Holford, N. H. G. (2013). The population pharmacokinetics of allopurinol and oxypurinol in patients with gout. European Journal of Clinical Pharmacology69(7), 1411-1421. doi: 10.1007/s00228-013-1478-8

Van Egmond, R., Barclay, M. L., Chin, P. K. L., Sies, C. W., & Florkowski, C. M. (2013). Biological variation of thiopurine methyltransferase enzyme activity: When has a significant change taken place?Annals of Clinical Biochemistry50(5), 473-478. doi: 10.1177/0004563212473441

Nasir, B. F., Griffiths, L., Nasir, A., Roberts, R., Barclay, M., Gearry, R., & Lea, R. A. (2013). Perianal disease combined with NOD2 genotype predicts need for IBD-related surgery in Crohn's disease patients from a population-based cohort. Journal of Clinical Gastroenterology47(3), 242-245. doi: 10.1097/MCG.0b013e318258314d

Nasir, B. F., Griffiths, L. R., Nasir, A., Roberts, R., Barclay, M., Gearry, R. B., & Lea, R. A. (2013). An envirogenomic signature is associated with risk of IBD-related surgery in a population-based Crohn’s disease cohort. Journal of Gastrointestinal Surgery17(9), 1643-1650. doi: 10.1007/s11605-013-2250-1

Korell, J., Stamp, L. K., Barclay, M. L., Dalrymple, J. M., Drake, J., Zhang, M., & Duffull, S. B. (2013). A population pharmacokinetic model for low-dose methotrexate and its polyglutamated metabolites in red blood cells. Clinical Pharmacokinetics52(6), 475-485. doi: 10.1007/s40262-013-0052-y

Koning, M., Ailabouni, R., Gearry, R. B., Frampton, C. M. A., & Barclay, M. L. (2013). Use and predictors of oral complementary and alternative medicine by patients with inflammatory bowel disease: A population-based, case-control study. Inflammatory Bowel Diseases19(4), 767-778. doi: 10.1097/MIB.0b013e31827f27c8

International Multiple Sclerosis Genetic Consortium (IMSGC), and also Mason, D., Barclay, M., Roberts, R., & Gearry, R. (2013). Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nature Genetics45(11), 1353-1360. doi: 10.1038/ng.2770

Falvey, J. D., Bentley, R. W., Merriman, T. R., Hampton, M. B., Barclay, M. L., Gearry, R. B., & Roberts, R. L. (2013). Macrophage migration inhibitory factor gene polymorphisms in inflammatory bowel disease: An association study in New Zealand Caucasians and meta-analysis. World Journal of Gastroenterology,19(39), 6656-6664. doi: 10.3748/wjg.v19.i39.6656

Chin, P. K. L., Vella-Brincat, J. W. A., Walker, S. L., Barclay, M. L., & Begg, E. J. (2013). Dosing of dabigatran etexilate in relation to renal function and drug interactions at a tertiary hospital. Internal Medicine Journal43(7), 778-783. doi: 10.1111/imj.12170

Beaudoin, M., Goyette, P., Boucher, G., Lo, K. S., Rivas, M. A., Stevens, C., … and also Barclay, M., Gearry, R., Roberts, R. (2013). Deep resequencing of GWAS loci identifies rare variants in CARD9,IL23R and RNF186 that are associated with ulcerative colitis. PLoS Genetics9(9), e1003723. doi: 10.1371/journal.pgen.1003723


Journal - Research Other

Roberts, R. L., Wallace, M. C., Seinen, M. L., Krishnaprasad, K., Chew, A., Lawrance, I., … Barclay, M. L. (2014). PACSIN2 does not influence thiopurine-related toxicity in patients with inflammatory bowel disease [Letter]. American Journal of Gastroenterology109, 925-927. doi: 10.1038/ajg.2014.89