News
Giving T Cells a GPS for Colorectal Cancer
Researchers at the University of Colorado are testing a new CAR-T cell therapy for advanced colorectal cancer. CAR-T therapy works by taking a patient’s own T cells and genetically modifying them so they can better recognise and attack cancer cells. You can think of it like giving the immune system a new GPS system that helps T cells find their target.
In this modern approach, the CAR-T cells are designed to recognise B7-H3, a protein found on many colorectal cancer cells. But the researchers are also targeting IL-8, a molecule in the tumour environment that can help cancer grow and make it harder for immune cells to work effectively. By attacking both the cancer cells and the environment that helps protect them, researchers hope to give CAR-T cells a better chance of fighting colorectal cancer.
Article: https://www.eurekalert.org/news-releases/1143707
Photo Source: https://www.cancer.gov/about-cancer/treatment/research/car-t-cells